• Down syndrome is a chromosomal disorder caused by an error in cell division that results in the presence of an additional third chromosome 21 or "trisomy 21."

• Named after John Langdon Down, the first physician to identify the syndrome.

• Down Syndrome usually causes delays in physical, intellectual and language development.

• Down syndrome is one of the leading causes of mental retardation - it is not related to race, nationality, religion or socioeconmic status.

• The incidence of Down syndrome is estimated to be 1 in every 600 - 800 live births.

• While the likelihood of giving birth to a child with Down syndrome increases with maternal age; neverless, 80% of babies with Down syndrome are born to women under 35 years of age, as women in that age group give birth to more babies overall.

• There is a wide variation in mental abilities, behavior and physical development in individuals with Down syndrome. Each individual has his/her own unique personality, capabilities and talents.

• 30-50% of the individuals with Down syndrome have heart defects and 8-12% have gastrointestinal tract abnormalities present at birth. Most of these defects are now correctable by surgery.

• Most people with Down syndrome have IQ's that fall in the mild to moderate range of retardation. Some are so mildly affected that they can live independently and be gainfully employed.

• Individuals with Down syndrome benefit from loving homes, early intervention, special education, appropriate medical care and positive public attitudes.